Inhibitory activity and cholesterol content of mouse and human ApoB-100 sera fractions.

Left columns: Shown are the average EC50 values, SD and fold-change in EC50 values for PLY treated with mouse or human sera (human serum was depleted of PLY antibodies), ApoB-100-depleted serum, ApoB-100 pellet (resuspended in PBS) or PBS alone. Results from 3 independent assays are shown. Right columns: Average cholesterol concentrations and SD for human and mouse sera after ApoB-100-depletion and the ApoB-100 pellet. The PEG precipitated ApoB-100 particles were resuspended to the same volume as the original serum sample for comparative purposes. C, cholesterol. CE, cholesterol esters. Results from 2 independent assays are shown.Inhibitory activity and cholesterol content of mouse and human ApoB-100 sera fractions.