Top twenty interaction models.

This table summarizes the top twenty interaction models identified in the SAC study group. P-values reflect the overall significance of the association between the genotype combinations and having TB, after adjusting for the main effects of the SNPs and covariates. A model of type C indicates a candidate gene pair, and a model of type B indicates a biofilter gene pair. These models were validated in the Gambian study group set using multiple SNPs found within the same gene regions, and the SNP pairs and p-values of the highest scoring Gambian models are reported. For some of the models, no SNPs were available in the Gambian data set for one or both of the genes (blank entries).