Ddit4 deficiency leads to a defect in AE9a induced leukemia development
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP519286
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资源简介：
Our research indicated knock out of DDIT4 markedly suppresses leukemia initiation potential, leukemia maintenance and self-renewal of AE9a leukemia cells in vivo. To better understand the molecular mechanisms underlying the role of DDIT4 in self-renewal of LSC and leukemia initiation, we performed global gene expression profiling by RNA sequencing on AE9a-Ddit4+/+ and AE9a-Ddit4-/- leukemia cells. Overall design: Transcriptome sequencing of leukemia cells from AE9a-Ddit4+/+ and AE9a-Ddit4-/- mice.
创建时间：
2025-12-05
