Intrinsically Disordered proteins with Extensive Annotations and Literature

IDEAL (Intrinsically Disordered proteins with Extensive Annotations and Literature) is a collection of experimentally-verified intrinsically disordered proteins (IDPs) that cannot adopt stable globular structures under physiological conditions. IDEAL contains manually curated annotations on IDPs in locations, structures, and functional sites such as protein binding regions and post-translational modification sites together with references and structural domain assignments.

IDEAL（Intrinsically Disordered proteins with Extensive Annotations and Literature，即富含注释与文献的内在无序蛋白数据集）是一类经实验验证的内在无序蛋白（intrinsically disordered proteins, IDPs）的集合，此类蛋白在生理条件下无法形成稳定的球状高级结构。该数据集包含经人工整理的注释信息，涵盖IDPs的定位、结构特征以及功能位点（如蛋白结合区域与翻译后修饰位点），同时附带相关参考文献与结构域注释。

搜集汇总

背景与挑战

背景概述

IDEAL是一个专门收录实验验证的固有无序蛋白质（IDPs）及其无序区域（IDRs）的知识库，提供手动注释的结构与功能信息，包括蛋白质结合区域、翻译后修饰位点和液液相分离关联等。该数据库支持通过浏览、搜索和下载等方式访问数据，并包含生物过程图示和引用文献。