Crystal structure of wild type HIV-1 protease in complex with non-peptidic inhibitor, GRL007
收藏Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/4i8w
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of wild type HIV-1 protease in complex with non-peptidic inhibitor, GRL007 Descriptor: 4-{[(2R,3S)-3-({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl}amino)-2-hydroxy-4-phenylbutyl](2-methylpropyl)sulfamoyl}benzoic acid, Protease Authors: Yedidi, R.S, Palmer, I, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. Deposit date: 2012-12-04 Release date: 2013-07-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.96 Å) Cite: P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety. Antimicrob.Agents Chemother., 57, 2013
创建时间：
2012-12-04
