Crystal structure of p38 alpha MAP kinase in complex with a novel isoform selective drug candidate
收藏Protein Data Bank Japan2024-11-27 更新2026-03-21 收录
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Crystal structure of p38 alpha MAP kinase in complex with a novel isoform selective drug candidate Descriptor: 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, 6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine, CHLORIDE ION, ... Authors: Grum-Tokars, V.L, Minasov, G, Roy, S.M, Anderson, W.F, Watterson, D.M. Deposit date: 2014-08-14 Release date: 2015-02-25 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Targeting human central nervous system protein kinases: An isoform selective p38 alpha MAPK inhibitor that attenuates disease progression in Alzheimer's disease mouse models. ACS Chem Neurosci, 6, 2015
创建时间：
2014-08-14
