Mortality and outcomes of Streptococcus suis infection and economic burden in Thailand

Streptococcus suis (S. suis) is an emerging zoonosis and a leading cause of adult bacterial meningitis in many developing countries. The disease is endemic in Southeast Asia mainly affecting men of working age. In Thailand, S. suis infection is an important health issue and one of the most common causes of bacterial meningitis with a high prevalence in the northern region due to cultural food habits involving consumption of raw pork. To date, much uncertainty remains regarding the understanding of S. suis clinical manifestations and treatment responses as well as gaps between different settings. This Ph.D project aimed to explore insights on risk factors, clinical manifestations and outcomes of S. suis infection as well as to quantify the burden of disease and its economic impact on years of life lost, quality of life and work productivity in Thailand.