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Transcriptomic (RNAseq) analysis of reovirus-induced host responses in mesenteric lymph node of interferon alpha/beta receptor (IFNabR) knockout and WT mouse.

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Analysis of reovirus-induced host responses at the level of gene expression. Results provide insights into how reovirus infection breaks tolerance to dietary antigens and promotes the development of celiac disease. Overall design: Total RNA obtained from mesenteric lymph node from WT and IFNabR KO mouse, and subjected to 48 hours stimulation with Reoviruses T1L or T3D-RV compared to Sham.

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2018-08-16
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