five

Longitudinal single-cell dynamics in chronic lymphocytic leukemia mirror disease history

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP302344
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Longitudinally sampled peripheral blood samples of 9 CLL patients were subjected to single cell RNA sequencing before and at relapse after chemotherapy with fludarabine, cyclophosphamide and rituximab (FCR); allogeneic hematopoietic stem cell transplantation (RIC allo-HSCT); ibrutinib treatment, or before and after transformation to Richter's syndrome. Overall design: Mononuclear cells from peripheral blood and bone marrow were obtained from nine human patients diagnosed with chronic lymphocytic leukemia and sequenced using scRNA-seq on the 10x platform
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2024-01-18
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