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Cryptic transcription is the primary driving force for nucleosome instability in Spt16 mutant cells

Alliance of Genome Resources2026-08-01 收录

核小体不稳定性

转录调控

数据链接：

https://www.yeastgenome.org/dataset/GSE66215 数据链接链接失效反馈

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FACT consists of two essential subunits Spt16 and Pob3 and is a histone chaperone

应用场景：

转录调控

癌细胞研究

Liver receptor homolog-1 (NR5A2) is an orphan nuclear receptor whose expression is essential for normal liver, intestine, and pancreas function. Nuclear receptors are ligand regulated transcription fa

DataCite Commons2020-09-04 更新60

VCaP_FOXA1_Dex_rep2

前列腺癌分子机制

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VCaP_FOXA1_Dex_rep2

DataCite Commons2023-03-09 更新20

Effect of Twist-box mutation on gene expression induced by Twist1 overexpression

癌症转移机制

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Twist1 is a transcription factor that induces EMT and drives metastasis in prostate cancer. We examined global gene expression in Myc-CaP mouse prostate cancer cells following overexpression of Twist1

NIAID Data Ecosystem10

Regulon-Specific Control of Transcription Elongation across the Yeast Genome

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功能基因组学

Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide studies have shown that transcriptional pausing during elongation is a frequ

NIAID Data Ecosystem30

MEF2C and EBF1 Co-regulate B Cell-Specific Transcription

B细胞分化

转录调控

Hematopoietic stem cells are capable of self-renewal or differentiation along three main lineages: myeloid, erythroid, and lymphoid. One of the earliest lineage decisions for blood progenitor cells is

Figshare2016-02-24 更新10

Cryptic transcription is the primary driving force for nucleosome instability in Spt16 mutant cells

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