Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle and RNA polymerase II mediated transcription. Several pharmacological CDK inhibitors are currently in clinical trials as potential
Supplementary data for the "Phosphorylation-induced structural dynamics of SARS-CoV-2 nucleocapsid protein" manuscript. In this work we performed 12 atomistic molecular dynamics simulations. The folde
The potential mechanism of ZX-7101 against influenza viruses is unknown. In this study, Transcriptome analysis demonstrated that ZX-7101 could directly inhibit viral replication and therefore affecte
