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cfDNA in Hereditary And High-Risk Malignancies (CHARM)

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NIAID Data Ecosystem2026-05-01 收录
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https://www.omicsdi.org/dataset/ega/EGAS00001006539
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Our goal is to improve early cancer detection by developing a blood test to predict cancer development in carriers using circulating DNA. As carriers develop cancer, they may have pre-cancerous cells which release this DNA into the blood (cell-free DNA; cfDNA), which can be detected with novel genetic technologies. We propose to use three complementary cfDNA assays:shallow whole genome sequencing (sWGS), Liquid-Biopsy Sequencing (LB-Seq) and Cell-free Methylated DNA Immunoprecipitation and High-throughput Sequencing (cfMeDip-Seq) for early cancer detection.EGA study EGAS00001006539
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2023-06-07
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