†: Colon is defined as right colon, transverse colon, left colon, sigmoid colon, rectosigmoid transition zone. Colon*: Proximal tumor is defined as right colon and transverse colon; distal tumor is de
Aim: This first-in-human study evaluated safety and efficacy of CD40 agonist MEDI5083 with durvalumab in patients with advanced solid tumors. Methods: Patients received MEDI5083 (3–7.5 m
n this double-blind, randomized controlled trial, the case group received the standard care regimen for PONV (dexamethasone 10 mg, ondansetron 4 mg, and metoclopramide 10 mg) plus prophylactic oral ap