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Effects of losmapimod on non-specific inflammatory response in aged skin.

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NIAID Data Ecosystem2026-04-30 收录
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We have previously demonstrated older skin exhibits increased sterile inflammation 6 hours after saline-injection. In this work, we examined whether p38MAPK inhibitor in vivo would attenuate this non-specific inflammatory response towards saline in elder individuals (=65 years). Overall design: Skin mRNA profiles 6 hours after saline injection were studied before and after losmapimod treatment.

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2023-01-11
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