iPSC-derived hypoimmunogenic T cells enriched with tissue resident memory T cells powerfully attack cervical cancer
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE237456
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We generated HLA-edited functionally rejuvenated human papilloma virus-specific CTLs (HPV-rejTs). These rejTs successfully suppressed recipient immune rejection, while retaining more robust cytotoxicity than that of original CTLs. To clarify this, single-cell RNA sequencing was performed. Original HPV-CTL clone and HLA-editied HPV-rejTs were generated then analyzed using scRNA-seq
创建时间：
2024-01-17
