THPdb2: compilation of FDA approved therapeutic peptides and proteins

THPdb2: Compilation of FDA Approved Therapeutic Peptides and Proteins Welcome to the official repository and documentation overview for THPdb2, an updated and significantly expanded version of the original THPdb. This manually curated database serves as a comprehensive knowledge base for all types of US-FDA approved protein-based drugs, including peptides, polypeptides, monoclonal antibodies, and biosimilar proteins. Web Server: https://webs.iiitd.edu.in/raghava/thpdb2/ Git Hub: https://github.com/sudhanshus-hash/THPdb2 Citation Jain, S., Gupta, S., Patiyal, S., & Raghava, G. P. S. (2024). THPdb2: compilation of FDA approved therapeutic peptides and proteins. Drug Discovery Today, 29(7), 104047. https://doi.org/10.1016/j.drudis.2024.104047 About the Database THPdb2 was developed to provide an integrated resource for the rapidly growing field of protein therapeutics. In the seven years since the inception of the original THPdb, the number of FDA-approved protein drugs has increased significantly. THPdb2 contains three times more information than its predecessor, helping researchers annotate and understand the therapeutic potential of proteins. The database integrates data from: Primary Literature: Meticulously collected and curated from research publications. External Repositories: Data sourced from DrugBank, PubChem, and UniProt.