Transcriptome analysis of mouse Cnot6l-/- preovulatory oocytes (GV), ovulated eggs (MII), and 1-cell zygotes

We profiled transcriptomes from Cnot6l deadenylase knock-out mouse GV oocytes, MII eggs and 1-cell zygotes in order to analyse its function during the oocyte-to-embryo (OET) transition. Transcriptome of wild-type golden hamster GV oocytes was also profiled. bulk RNA-seq of 20 samples: - 3 replicates of each WT and Cnot6l knock-outs in 3 mouse developmental stages (GV, MII, 1-cell) - 2 replicates of WT golden hamster GV oocytes