Treatment outcomes in prisons in the FSU.

aSee Text S1 for summary of literature review and methodology of estimation of rates and proportions of individuals with outcomes. Based on an exponential assumption, we applied an exponential transform to convert probabilities into time-constant rates. When more than one event could occur from a given health state, we computed the overall weekly likelihood of any event occurring based on the sum of the weekly rates relevant to that health state and then used the ratio of a particular rate to the sum of the relevant rates to determine the proportion of events of each type that occurred from that health state within the weekly interval.bAcquisition of MDR-TB during first-line (DOTS) treatment (σ) can occur via amplification of existing resistance, which is static (F), or through reinfection, which is dynamic and depends on the local force of infection among those being treated with standard first-line therapy (not shown). The above computed proportions of individuals with outcomes are for illustrative purposes; they exclude cases of reinfection in their estimation and are based only on these static parameters. This implies that when MDR-TB transmission is higher, treatment success and treatment failure proportions for non-MDR-TB will be lower than shown in the table, since reinfection is a more substantial competing risk.