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Crystal structure of integrin-linked kinase (ILK) in complex with alpha-parvin and a cyano-quinoline ligand

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Protein Data Bank Japan2026-06-24 更新2026-08-24 收录
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Crystal structure of integrin-linked kinase (ILK) in complex with alpha-parvin and a cyano-quinoline ligand Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-6-piperazin-1-yl-quinoline-3-carbonitrile, ... Authors: Abdul Azeez, K.R, Greco, F.A, Knapp, S. Deposit date: 2025-12-17 Release date: 2026-06-03 Last modified: 2026-06-24 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Identification and Validation of 3-Cyano-Quinoline Ligands Targeting Integrin-Linked Kinase (ILK). J.Med.Chem., 69, 2026

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2025-12-17
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