NanDeSyn

To facilitate community-based annotation and mining of the rapidly accumulated functional genomics resources, we have initiated an international consortium and present a comprehensive, multi-omics resource database named Nannochloropsis Design and Synthesis (NanDeSyn; http://nandesyn.single-cell.cn). Via the Tripal toolkit, it featured user friendly interfaces hosting genomic resources with gene annotations, and transcriptomic and proteomic data for six Nannochloropsis species, including two updated genomes of N. oceanica IMET1 and N. salina CCMP 1776. Toolboxes for search, Blast, synteny view, enrichment analysis, metabolic pathway analysis, genome browser, etc. were also included. In addition, functional validation of genes was indicated based on phenotypes of mutants and relevant bibliography. Furthermore, epigenomic resources were also incorporated, especially for small RNA-Seq including miRNAs and circRNAs.为便于对快速积累的功能基因组学资源开展社区化注释与挖掘工作，我们发起了一项国际联盟，并推出了一款综合性多组学资源数据库——微拟球藻设计与合成（Nannochloropsis Design and Synthesis，缩写为NanDeSyn；访问地址：http://nandesyn.single-cell.cn）。借助Tripal工具包，该数据库搭载了用户友好的交互界面，收录了6种微拟球藻的带基因注释的基因组资源，以及转录组与蛋白质组数据，其中包含两份更新后的基因组：海洋微拟球藻（N. oceanica）IMET1与盐生微拟球藻（N. salina）CCMP 1776。该数据库还集成了搜索、BLAST、共线性可视化、富集分析、代谢通路分析、基因组浏览器等工具集。此外，该数据库还基于突变体表型数据与相关文献，提供了基因功能验证相关信息。进一步地，数据库还纳入了表观基因组学相关资源，尤其是包含微小RNA（miRNAs）与环状RNA（circRNAs）在内的小RNA测序（small RNA-Seq）数据。

搜集汇总

背景与挑战

背景概述

NanDeSyn是一个综合性的多组学资源数据库，专注于六种微藻物种，提供基因组、转录组和蛋白质组数据，并集成包括搜索、Blast、富集分析和基因组浏览器在内的多种分析工具。该数据库还收录了基于突变体表型的基因功能验证数据以及表观基因组资源，如小RNA测序数据。