Genetics of spontaneous abortion: heritable aspects of common gynecological disorders Genetics of spontaneous abortion: heritable aspects of common gynecological disorders

Contributor(s): Simpson, Joe Leigh, 1943- Academy of Health Sciences (U.S.) Publication: Fort Sam Houston, Tex. : The Academy ; [for loan by its Health Sciences Media Division, 1975] Language(s): English Format: Moving image Subject(s): Abortion, Spontaneous -- genetics Genital Diseases, Female -- genetics Abstract: This lecture by Dr. Joe Leigh Simpson was recorded at the 24th Annual Armed Forces Seminar on Obstetrics and Gynecology in October 1975 in San Antonio. Spontaneous abortions can be divided into three major groups: embryos that are in the preclinical stage of less than four to six weeks and therefore not identified, clinically identified embryos in the first trimester, and abortions and stillbirths that occur in the second or third trimester. Doctors have found that unviable, morphologically abnormal embryos are quite common in the preclinical stage. This can be attributed to chromosomal abnormalities, which account for about half of all cases. The incidence of such an abortion increases the risk of recurrence, and another factor contributing to this may be genetic incompatibilities between the maternal and paternal sides. The second part of the lecture focuses on common heritable factors in gynecological disorders, including polygenic conditions, infertility, Stein-Leventhal syndrome, and cancer. Copyright: The National Library of Medicine believes this item to be in the public domain. (More information) Extent: 029 min. Color: Color Credits: Joe Leigh Simpson. Technique: Other NLM Unique ID: 7603050A (See catalog record) OCLC no.: 10243353 Permanent Link: http://resource.nlm.nih.gov/7603050A