five

Kinase domain of cSrc in complex with Dasatinib

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Protein Data Bank Japan2023-11-01 更新2026-03-21 收录
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资源简介:
Kinase domain of cSrc in complex with Dasatinib Descriptor: GLYCEROL, N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Proto-oncogene tyrosine-protein kinase Src Authors: Grutter, C, Kluter, S, Rauh, D. Deposit date: 2009-02-05 Release date: 2009-06-02 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc J.Med.Chem., 52, 2009
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2009-02-05
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