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Methylation signature of pluripotent stem cells

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NIAID Data Ecosystem2026-05-09 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE55006
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Two iPSC clones (iKCL004 and iKCL011) were compared with parental human neonatal foreskin fibroblasts BJ (ATCC, CRL-2522) as a negative and hESC line KCL034 as a positive control Biological triplicates for each line were analyses for epigenome-wide methylation (>480,000 CpG sites) using Infinium Human Methylation 450 BeadChip Kit (Illumina). Bisulphite converted DNA (500 ng/sample) from the 12 samples (3 biological replicates from 4 lines) were hybridized to the Infinium Human Methylation 450 BeadChip Kit (Illumina)
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2017-02-10
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