File S1 - Adaptive Gene Regulation in the Striatum of RGS9-Deficient Mice

Contains the following files. Table S1. Primers used for qPCR. (fwd = forward, rev = reverse). Table S2. OntoExpress analysis of genes differentially regulated in RGS9-deficient mice. MAS5-processed microarray data were filtered for probe sets ≥3 present calls. Probe sets that were significantly regulated (**P≤0.01) between wt and RGS9-deficient mice were subjected to gene ontology analysis. The table shows the statistically regulated biological processes ranked by the total number of genes regulated. Table S3. Gene Set Enrichment Analysis (GSEA) of differentially expressed genes in RGS9-deficient mice and wild-type mice. Table S4. Expression analysis of selected genes by qPCR. The table shows all transcripts the concentration of which were determined by qPCR in striata of wildtype and RGS9-deficient mice. Gene expression data are given as 2−ΔΔCT ± SEM with the sample size in parentheses. Furthermore, microarray data and the affiliation to LTD, LTP and/or Ca2+ signaling pathway are listed for each transcript. *P≤0.05, **P≤0.01, ***P≤0.001. Table S5. Microarray expression analysis of striata of RGS9-deficient mice. The table shows all significant regulated transcripts with a fold-change ≤0.5 or ≥1.5. *P≤0.05, **P≤0.01, ***P≤0.001. (DOC)