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Crystal structure of human TAK1/TAB1 fusion protein in complex with ligand 11c

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Protein Data Bank Japan2023-11-08 更新2026-03-21 收录
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Crystal structure of human TAK1/TAB1 fusion protein in complex with ligand 11c Descriptor: N-[5-(4-methylpiperazine-1-carbonyl)[1,1'-biphenyl]-2-yl]-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-7-carboxamide, TAK1 kinase - TAB1 chimera fusion protein Authors: Irie, M, Nakamura, M, Fukami, T.A, Matsuura, T, Morishima, K. Deposit date: 2016-04-19 Release date: 2016-07-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of a potent and highly selective transforming growth factor beta receptor-associated kinase 1 (TAK1) inhibitor by structure based drug design (SBDD) Bioorg.Med.Chem., 24, 2016
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2016-04-19
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