Comparative Efficacy of Preventive vs. Therapeutic Resveratrol in Modulating Gut Microbiota and Alleviating Inflammation in DSS-Induced Colitis

This study investigates the comparative efficacy of preventive versus therapeutic resveratrol administration in modulating gut microbiota and alleviating inflammatory bowel disease (IBD). Using a DSS-induced murine colitis model, we analyzed gut microbial diversity via 16S rRNA gene sequencing and host metabolic responses. Our findings aim to elucidate resveratrol's potential as a microbiome-targeted intervention for IBD, providing mechanistic insights into its preventive and therapeutic applications.