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Total Synthesis of (±)-Minimiflorin and Its Na+/K+‑ATPase and H+/K+‑ATPase Inhibitory Activities

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Figshare2025-06-29 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Total_Synthesis_of_-Minimiflorin_and_Its_Na_sup_sup_K_sup_sup_ATPase_and_H_sup_sup_K_sup_sup_ATPase_Inhibitory_Activities/29433412
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We have now successfully synthesized (±)-minimiflorin, known as a natural product with H+/K+-ATPase inhibitory activities, via two routes. Considering the structural similarity between H+/K+-ATPase and Na+/K+-ATPase, with 60% sequence homology, we measured the Na+/K+-ATPase inhibitory activities of our synthesized (±)-minimiflorin and found that it has Na+/K+-ATPase inhibitory activities.
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2025-06-29
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