Total Synthesis of (±)-Minimiflorin and Its Na+/K+‑ATPase and H+/K+‑ATPase Inhibitory Activities
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We have now successfully synthesized (±)-minimiflorin, known as a natural product with H+/K+-ATPase inhibitory activities, via two routes. Considering the structural similarity between H+/K+-ATPase and Na+/K+-ATPase, with 60% sequence homology, we measured the Na+/K+-ATPase inhibitory activities of our synthesized (±)-minimiflorin and found that it has Na+/K+-ATPase inhibitory activities.
创建时间：
2025-06-29
