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The stereochemical configurations at the C2 and C6 carbons of hydroxynorketamine (HNK) affect the concentration-dependent decrease in intracellular D-Ser concentration in PC-12 cells.

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Figshare2016-04-25 更新2026-04-29 收录
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https://figshare.com/articles/dataset/The_stereochemical_configurations_at_the_C2_and_C6_carbons_of_hydroxynorketamine_HNK_affect_the_concentration_dependent_decrease_in_intracellular_D_Ser_concentration_in_PC_12_cells_/3191011
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The relative pharmacological activity (αD) is derived by IC50(trans-isomer)/IC50(cis-isomer). The IC50 values are expressed as means ± SD, n = 3 independent experiments.
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2016-04-25
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