Targeting Histone Demethylase LSD1 for Treatment of Deficits in Autism Mouse Models [ChIP-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE193404
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We performed chromatin immunoprecipitation sequencing (ChIPseq) to profile genome-wide occupancy of H3K4me2 in PFC from WT mice and Shank3 +/∆C Tau mice. Examination of the transcriptional changes of target genes related to the alteration of H3K4me2 from isolated nuclei of 6-week-old Shank3 +/∆C and 6-week-old control (C57BL/6 x C3H) mice from PFC tissue were compared.
创建时间:
2022-01-14



