CD34+CD38–stem cell frequencies and their marker expression in the ALDH^bright and ALDH^low compartment in CD34-positive AML.

Detection of immunophenotypic aberrancies in CD34+CD38– ALDHbright and ALDHlow compartments of CD34-positive AML. *The percentage of CD34+CD38– cells in the total ALDHbright or ALDHlow compartments is indicated. &in the ALDHbright CD34+CD38– compartment the aberrant marker expression, both CLL-1 and lineage markers, is indicative for the neoplastic character of the cells. #Percentage expression does not quantitatively correlate with % of neoplastic cells: a shift in fluorescence of a total cell population may result e.g. in 50% marker expression based on normalization by isotype controls of negative cell populations. ‡data in between parenthesis represent number of cells in cases where there is <25 cells positive for a marker.