C.elegans gene expression study for single, double or triple genetic perturbations of regulators in AMPK, Insulin and TOR pathway

We use genetic manipulations of regulators representing different pathways to examine whether transcriptomes progressively resemble dietary restriction when multiple regulators are perturbed.本研究通过对代表不同通路的调控因子（regulators）实施遗传操作（genetic manipulations），旨在探究当多个调控因子发生扰动时，转录组（transcriptome）是否会逐步趋近于膳食限制（dietary restriction）条件下的状态。