Dynamic profiling of histone Kcr and Kla during neural differentiation in P19 embryonal carcinoma cells. Dynamic profiling of histone Kcr and Kla during neural differentiation in P19 embryonal carcinoma cells

To gain a deeper insight into dynamic changes of histone lysine crotonylation and lactylation during embryonic neurogenesis, ChIP-seq, ATAC-seq and RNA-seq were performed to analyze the genome-wide changes of histone Kcr and Kla in the P19 embryonal carcinoma cells. Overall design: ChIP-seq, ATAC-seq and RNA-seq were both performed with two biological replicates, and sequenced on Illumina NovaSeq 6000 platform.