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A mouse model of the most aggressive subgroup of human medulloblastoma [HT_MG-430_PM]

ChEBI2012-02-29 更新2026-07-21 收录

母细胞瘤模型

神经肿瘤临床前研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-33200 数据链接链接失效反馈

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资源简介：

A mouse model of the most aggressive subgroup of human medulloblastoma [HT_MG-430_PM]

应用场景：

创建时间：

2012-02-29

母细胞瘤模型

CRISPR系统

Myc-driven Group 3 (G3) medulloblastoma (MB) is the most aggressive tumor among the four subgroups classified by transcriptome, genomic landscape and clinical outcomes. Several successful mouse model

NIAID Data Ecosystem70

Novel MYC-driven medulloblastoma models generated by CRISPR activation of endogenous Myc

母细胞瘤模型

CRISPR基因激活

Myc-driven Group 3 (G3) medulloblastoma (MB) is the most aggressive tumor among the four subgroups classified by transcriptome, genomic landscape and clinical outcomes. Several successful mouse model

NIAID Data Ecosystem60

Remodeling Group 3 medulloblastoma: MYC overexpression alone transforms progenitors of astrocytes and granule neurons in the postnatal cerebellum

母细胞瘤模型

肿瘤发生机制

Group 3 medulloblastoma is often associated with MYC amplification or overexpression, while whether MYC overexpression alone is sufficient to induce tumorigenesis is unknown and the cell type(s) which

NIAID Data Ecosystem50

Medulloblastoma Pgbd5 Mutator

癌症基因组数据

母细胞瘤模型

Somatic DNA rearrangements induced by Pgbd5 in mouse medulloblastoma models

NIAID Data Ecosystem70

Novel MYC-driven medulloblastoma models generated by CRISPR activation of endogenous Myc. Mus musculus

母细胞瘤模型

CRISPR肿瘤基因激活

Myc-driven Group 3 (G3) medulloblastoma (MB) is the most aggressive tumor among the four subgroups classified by transcriptome, genomic landscape and clinical outcomes. Several successful mouse models

NIAID Data Ecosystem50

A mouse model of the most aggressive subgroup of human medulloblastoma [HT_MG-430_PM]

资源简介：

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