The crystal structure of DYRK1a with a bound pyrido[2,3-d]pyrimidine inhibitor
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The crystal structure of DYRK1a with a bound pyrido[2,3-d]pyrimidine inhibitor Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, N-(5-{[(1R)-3-amino-1-(3-chlorophenyl)propyl]carbamoyl}-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide, PENTAETHYLENE GLYCOL, ... Authors: Lukacs, C.M, Janson, C.A, Garvie, C, Liang, L. Deposit date: 2013-09-15 Release date: 2013-12-11 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Pyrido[2,3-d]pyrimidines: Discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
创建时间：
2013-09-15
