Transcriptional comparison of Testicular Adrenal Rest Tumors with fetal and adult tissues

By comparing the transcriptome of TART with fetal- and adult- testis and adrenal tissues, this study aimed to unravel the origin of TART. Sixteen TART samples were previously obtained from patients with CAH (n=7) or recurrent Cushing’s Disease (n=1). Adult adrenal (n=11), adult testis (n=10), fetal adrenal (n=13), and fetal testis (n=5) tissues were obtained. Transcriptomic comparisson of Testicular Adrenal Rest Tumors (TART) (n=16) obtained from patients with Congenital Adrenal Hyperplasia (n=7) or recurrent Cushing's Disease (n=1) with adult adrenal (n=11), adult testis (n=10), fetal adrenal (n=13), and fetal testis (n=5) tissues, and Leydig Cell Tumors (n=7).