PDIR

The Predicted Drosophila Interactome Resource (PDIR) is prepared through the integration of six types of evidence for functional gene associations from 10 public databases. It includes 102,835 gene associations, including predicted 98,056 functional associations and 4,779 experimentally reported interactions. These 102,835 functional associations are expected to cover ~22.6% of the protein-protein interactions of Drosophila. Approximately 50.5% of these functional associations are expected to represent protein-protein interactions.预测型果蝇互作组资源（Predicted Drosophila Interactome Resource, PDIR）通过整合10个公共数据库中的6类功能基因关联证据构建而成。该资源共收录102,835条基因关联记录，其中包含98,056条预测功能关联与4,779条经实验报道的互作关系。上述102,835条功能关联预计覆盖果蝇约22.6%的蛋白质-蛋白质互作（protein-protein interactions），其中约50.5%的功能关联预计对应蛋白质-蛋白质互作。

搜集汇总

背景与挑战

背景概述

PDIR数据集通过整合10个公共数据库中的六类证据，构建了一个果蝇功能基因关联网络，包含102,835个关联，其中预测功能关联98,056个，实验报告交互4,779个。这些关联预计覆盖果蝇蛋白质间相互作用的约22.6%，其中约50.5%代表蛋白质间相互作用，并基于此网络提供基因集连锁分析工具。