Transcriptional regulation of cell division and cytokinin response in Arabidopsis shoot apical meristem [ChIP-seq]

In plants, the phytohormone cytokinin plays a major role in promoting cell division. However, the molecular mechanisms underlying cytokinin stimulated cell proliferation remain poorly understood. Here we show that, in the meristems of Arabidopsis thaliana, two transcriptional factors, MYB3R1 and MYB3R4, are master regulators of mitotic cell cycle gene expression and cytokinin response. Overall design: ChIP-seq was carried out using dissected inflorescence meristems.