Amplicon sequencing files related to the design and evaluation of three deaminases (Ddd1, TadA8e, Sdd6), a reverse transcriptase, three nucleases (Cas9, Cas12a, Cas12n), and nuclear localization signa
Targeted amplicon sequencing of mouse and human cell lines following base editing with optimized base editing enzymes. Data reported in manuscript "Optimized base editing constructs enable efficient e
To study the tumor cell inhibition mechanism of our M@HLPC, we conducted RNA-sequencing (RNA-seq) analysis to identify differentially-expressed genes in U251 cells with M@HLPC treatment. In this exper
To identify the key genes that influence resistance in ESCC cells to cisplatin therapy, transfected cell lines with CRISPR library were screened under cisplatin pressure and then sequenced. In the con