c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program [CUT&RUN]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE137320
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资源简介:
The transcription factor c-Maf is an essential regulator of group 3 ILC homeostasis and effector plasticity. c-Maf limits acquisition of the type 1 program and conversion to the ILC1 fate through restraint of T-bet expression and function. Evaluation of differential H3K27ac and H3K27me3 histone marks in cohoused Maf-deficient NKp46+ ILC3. The CUT&RUN protocol was performed on replicate samples of NKp46+ ILC3 isolated from the small intestine lamina propria of Maf+/+ Il7r-Cre and Maf fl/fl Il7r-Cre mice.
创建时间:
2019-12-14



