T2W Atlas

CRL2025 T2W Atlas and Segmentations This is a spatio-temporal map of the developing fetal brain, from gestational age (GA) weeks 21 to 37, made from 194 reconstructed fetal T2-weighted brain images. Included are two sets of image segmentations: tissue segmentations with delineated borders between white and cortical gray matter (cortical plate), and regional parcellations which overlap the white-gray matter border. The tissue segmentation is further divided into two versions, one which splits white matter into subplate and intermediate zone (white matter zones; WMZ), and one that does not. WMZ segmentations are only supplied up to 32 weeks gestational age. Contents: t2w_GA*_atlas.nii.gz - T2-weighted atlas images t2w_GA*_tissue.nii.gz - Tissue segmentations t2w_GA*_tissueWMZ.nii.gz - Tissue segmentation with white matter zone division t2w_GA*_regional.nii.gz - Regional parcellation T2WAtlas_labelkey-tissue.txt - Label key for tissue segmentation T2WAtlas_labelkey-region.txt - Label key for regional segmentation Label keys can be loaded in ITK-SNAP Files in this data release were developed for research purposes and are not intended for medical or diagnostic use and have no warranty. The authors and distributors do not make any guarantees regarding the accuracy or usefulness of results generated from these tools or their derivatives and are not liable for any damages resulting from their use. Through this data use agreement, you agree to cite the DOI referring to this resource as well as the following papers: Bagheri, M., Velasco-Annis, C., Wang, J., Faghihpirayesh, R., Khan, S., Calixto, C., Jaimes, C., Vasung, L., Ouaalam, A., Afacan, O. and Warfield, S.K., 2025. An MRI Atlas of the Human Fetal Brain: Reference and Segmentation Tools for Fetal Brain MRI Analysis. arXiv preprint arXiv:2508.15034. Gholipour, A., Rollins, C.K., Velasco-Annis, C. et al. A normative spatiotemporal MRI atlas of the fetal brain for automatic segmentation and analysis of early brain growth. Sci Rep 7, 476 (2017). https://doi.org/10.1038/s41598-017-00525-w T2-weighted image reconstructions were performed using MIRTK construct-atlas: Schuh et al., “Unbiased construction of a temporally consistent morphological atlas of neonatal brain development”, bioRxiv, 2018. doi:10.1101/251512