BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair

ChEBI2012-09-30 更新2026-07-21 收录

DNA损伤修复机制

BRCA1

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35698 数据链接链接失效反馈

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资源简介：

BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair

创建时间：

2012-09-30

Supporting Data for ' Kinase Library Screen identified VRK3 as a Novel DNA Damage Factor '

CRISPRi筛选

DNA损伤修复机制

Data from the CRISPR library screen enabled us to isolate the target protein in this research. Using live-cell imaging, we were able to validate the involvement of the hits from the CRISPR library scr

DataCite Commons2023-08-10 更新280

Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice. Single Nucleotide Resolution Analysis of Nucleotide Excision Repair of Ribosomal DNA in Humans and Mice

DNA损伤修复机制

单核苷酸分辨率基因组学

In the present work we have applied analytical methods to map repair events in rDNA using data generated by the newly developed XR-seq genome-wide single nucleotide repair technology. We find that in

NIAID Data Ecosystem60

Roles for the Transcription Elongation Factor NusA in Both DNA Repair and Damage Tolerance Pathways in Escherichia coli. Escherichia coli

DNA损伤修复机制

转录偶联修复

Here we report our observations that have led us to propose that the transcription elongation factor NusA promotes a novel class of transcription-coupled repair (TCR) in addition to its previously pro

NIAID Data Ecosystem50

FAN1 R507H-PCNA-DNA_minimum-dataset

DNA损伤修复机制

冷冻电镜结构解析

This minimum cryo-EM dataset is used in the research of 'Structural and molecular basis of PCNA-activated FAN1 nuclease function in DNA repair'.

Figshare2025-02-10 更新70

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

酶-RNA复合物结构

DNA损伤修复机制

Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion)

NIAID Data Ecosystem50