Basonuclin-1 modulates epithelial plasticity and TGF-?1-induced loss of epithelial cell integrity [BNC1]

ChEBI2014-03-01 更新2026-07-21 收录

上皮-间质转化调控

分子细胞病理学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-54715 数据链接链接失效反馈

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Basonuclin-1 modulates epithelial plasticity and TGF-?1-induced loss of epithelial cell integrity [BNC1]

创建时间：

2014-03-01

Characterization of epigenomic and transcriptomic changes upon TGF-beta treatment in NMuMG cells [DnaseI-seq]

上皮-间质转化调控

染色质可及性分析

TGFβ cytokines have crucial roles in development, proliferation, tissue homeostasis, differentiation, and immune regulation. Consequently, alterations in TGFβ signaling underlie numerous diseases, inc

NIAID Data Ecosystem90

Foxf2 plays a dual role during TGFb-induced EMT by promoting apoptosis yet enabling cell junction dissolution and migration.

上皮-间质转化调控

转录因子功能分析

We have identified the transcription factor forkhead box protein F2 (Foxf2) to be upregulated in its expression during the EMT process and studied its functional contribution to EMT by siRNA-mediated

NIAID Data Ecosystem60

Figure S1 - Restoration of miR-1228* Expression Suppresses Epithelial-Mesenchymal Transition in Gastric Cancer

癌症分子机制

上皮-间质转化调控

Effect of miR-1228* on EMT in AGS cells. (A) Western blot analysis of epithelial marker E-cadherin and mesenchymal marker Vimentin in miR-1228* stable transfected AGS cells and control. (B) Transwell

NIAID Data Ecosystem50

Spatial Transcriptional Profile of the Chick and Mouse Endocardial Cushions Identify Novel Regulators of Endocardial EMT in vitro. Spatial Transcriptional Profile of the Chick and Mouse Endocardial Cushions Identify Novel Regulators of Endocardial EMT in vitro

发育生物学

上皮-间质转化调控

Objective: We developed an unbiased strategy to identify genes important in endocardial epithelial-to-mesenchymal transformation (EMT) using a spatial transcriptional profile. Methods and Results: End

NIAID Data Ecosystem60

TET1 regulates hypoxia-induced epithelial-mesenchymal transition through DNA demethylation (hMeDIP-Seq). Homo sapiens

缺氧响应基因

上皮-间质转化调控

In order to explore the status of DNA methylation in hypoxia response, we show that TET1, a DNA dioxygenase converting 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), regulates hypoxia-res

NIAID Data Ecosystem50

Basonuclin-1 modulates epithelial plasticity and TGF-?1-induced loss of epithelial cell integrity [BNC1]

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