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A Highly Stereoselective Organocatalytic Tandem Aminoxylation/Aza-Michael Reaction for the Synthesis of Tetrahydro-1,2-Oxazines

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/A_Highly_Stereoselective_Organocatalytic_Tandem_Aminoxylation_Aza_Michael_Reaction_for_the_Synthesis_of_Tetrahydro_1_2_Oxazines/2907121
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资源简介:
A facile stereoselective synthesis of multifunctionalized tetrahydro-1,2-oxazines (THOs) has been achieved by the organocatalyzed asymmetric tandem α-aminoxylation/aza-Michael reaction for the C−O/C−N bond formations in moderate to good yields with excellent diastereo- (>99:1 dr) and enantioselectivities (92% to >99% ee).
创建时间:
2008-10-16
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