Next Generation Sequencing Facilitates Quantitative Analysis of Dura macrophage Transcriptomes post adoptive T cell reconstitution of RAG-1 deficient mice II

The goal of this study was to compare transcriptional changes evoked by T cells cross talk with meningeal macrophages. Furthermore, the role of specific T cell subsets or selected cytokine deficiency were used to evaluate their role in regulating such transcriptional changes Overall design: Dural macrophage mRNA profiles post T cell reconstitution of RAG-1 deficient mice were generated by deep sequencing, in replicate, using Illumina HiSeq