Additional file 2: of Disease progression in women with X-linked adrenoleukodystrophy is slow

Individual clinical data: SF-36, EDSS and ALDS values. SF-36 values were compared with norm values for the Dutch population and corrected for gender and age. The SF-36 subdomain scores are expressed in Z scores, ranging from − 4 (lowest quality of life) to + 4 (highest quality of life). The SF-36 summary scores were linearly transformed to a range from 0 (lowest quality of life) to 100 (highest quality of life), with a mean of 50 and standard deviation of 10. The EDSS ranges from 0 (normal) to 10 (death). The ALDS scores are regression coefficients which were linearly transformed for interpretation, ranging from 10 (highest level of disability) to 89.47 (lowest level of disability). ALDS = AMC Linear Disability Scale; EDSS = Expanded Disability Status Scale; MCS = mental component summary; PCS = physical component summary; SF-36 = Short Form (36) Health Survey. (XLSX 21 kb)

个体临床数据：包括 SF-36、EDSS 以及 ALDS 的数值。SF-36 的评分与荷兰人群的常模进行了比较，并针对性别和年龄进行了校正。SF-36 的子领域评分以 Z 分数形式呈现，范围从 -4（生活质量最低）至 +4（生活质量最高）。SF-36 的综合评分通过线性转换，其范围从 0（生活质量最低）至 100（生活质量最高），均值为 50，标准差为 10。EDSS 的评分范围从 0（正常）至 10（死亡）。ALDS 评分代表回归系数，经过线性转换以便于解读，其范围从 10（残疾程度最高）至 89.47（残疾程度最低）。其中，ALDS 为 AMC 线性残疾量表（AMC Linear Disability Scale），EDSS 为扩展残疾状态量表（Expanded Disability Status Scale），MCS 为心理成分汇总（mental component summary），PCS 为生理成分汇总（physical component summary），SF-36 为简明健康调查表（Short Form (36) Health Survey）。（文件格式：XLSX，文件大小：21 kb）