Inhibitor Bound to A DFG-In structure of the Kinase Domain of CSF-1R
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Inhibitor Bound to A DFG-In structure of the Kinase Domain of CSF-1R Descriptor: Macrophage colony-stimulating factor 1 receptor, N~3~-(2,6-dichlorobenzyl)-5-(4-{[(2R)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl}phenyl)pyrazine-2,3-diamine, SULFATE ION Authors: Kamtekar, S, Day, J.E, Reitz, B.A, Mathis, K.J, Meyers, M.J. Deposit date: 2010-01-10 Release date: 2010-03-02 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode Bioorg.Med.Chem.Lett., 20, 2010
创建时间：
2010-01-10
