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Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease

ChEBI2014-07-01 更新2026-07-21 收录

等位基因特异性

复杂疾病遗传学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-56298 数据链接链接失效反馈

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Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease

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创建时间：

2014-07-01

等位基因特异性

基因组三维结构

DNA replication occurs in a defined temporal order known as the replication-timing (RT) program. RT is regulated during development in discrete chromosomal units, coordinated with transcriptional acti

NIAID Data Ecosystem70

Additional file 7 of Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs

癌症表观遗传学

等位基因特异性

Additional file 7: Table S6. ASM loci tested for validations by targeted bisulfite sequencing.

NIAID Data Ecosystem70

Additional file 8: of Population and allelic variation of A-to-I RNA editing in human transcriptomes

RNA编辑

等位基因特异性

In-house python scripts for the ASED analysis. List of command-line commands and python scripts to generate allele-specific alignments along with R code for paired statistical test. (GZ 12 kb)

NIAID Data Ecosystem40

Allele-specific ATAC-seq across 16 neural progenitor cell clones

等位基因特异性

细胞表观遗传调控

The two copies of a gene are canonically believed to be indistinguishable to the cell and are expressed in the same spatiotemporal manner in the absence of a loss-of-function mutation. Â The mechanism

NIAID Data Ecosystem70

ONT direct RNA sequencing Fast5 files from mouse embryonic stem cell (C57BL/6J x CAST/EiJ) Mettl3 Knockout

RNA表观遗传修饰检测与预测

等位基因特异性

We present a novel approach that leverages Oxford Nanopore direct RNA sequencing technology to detect allele-biased patterns of N6-methyladenosine (m6A) modifications in native mRNAs. Our approach uti

NIAID Data Ecosystem50

Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease

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