five

Expression of retrotransposons contributes to aging in Drosophila

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https://www.ncbi.nlm.nih.gov/sra/SRP384141
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资源简介:
We aimed to elucidate the mechanism by which retrotransposon (RT) knockdown extends female lifespan in drosophila. To do so we compared two, single RT (412 and Roo) shRNA knockdowns (KD) to a scrambled hairpin control. Overall design: We performed paired end RNA-sequencing on pooled thoraces from day 20 old female flies (F1-3) in triplicate. We used a scramble (scr) hairpin as a control to our 412 and Roo shRNA ubiqutious (Act5C) knockdown animals
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2023-07-13
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