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Impaired AGO2/miR-185-3p/NRP1 Axis Promotes Colorectal Cancer Metastasis

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA700817
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资源简介:
AGO2 is a master regulator of miRNA maturation, stability, and function. Knockdown of AGO2 may lead to reduced numbers of the mature miRNAs that regulate the expression of NRP1. To test this hypothesis, we performed miRNA sequencing of SW1116 AGO2-KD and AGO2-CON cells. Eighty-one miRNAs were significantly reduced, and 24 miRNAs were significantly increased in the AGO2-KD group.
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2021-02-09
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